Laser capture microdissection (LCM) is an automated sample preparation technique that enables isolation of specific cells from a mixed population under microscopic visualization. This technique of isolating a pure sample from a heterogeneous mixture allows for more efficient and accurate results with downstream microgenomics applications such as next-generation sequencing, Sanger sequencing, PCR, and proteomics.
Arcturus® LCM System
Applied Biosystems™ ArcturusXT™ LCM System is a unique microdissection system that combines the power of infrared (IR) laser capture and ultraviolet (UV) laser cutting in one modular platform. The solid-state IR laser delivers a gentle capture technique that preserves the overall biomolecular integrity of cells, and is ideal for both single cells and small numbers of cells. The solid-state UV laser permits superior speed and precision, and is well suited for microdissecting dense tissue structures, and capturing large numbers of cells.
- Dual laser system—enables a wide range of applications ranging from single-cell isolation to large biopsy extractions
- Exclusive, gentle IR laser capture microdissection—preserves morphology of isolated samples and integrity of biological material for downstream applications
- Intuitive software—enables rapid isolation of specific cells in five simple steps, provides quality control feature that allows users to visualize collected sample
- Flexible sample prep—wide range of slide types and sample preparation formats supported