DynaChrom™ Single-Use Chromatography System

The Thermo Scientific DynaChrom Chromatography System brings innovation, scalability, and robust automation to single-use downstream bioprocessing. It offers modular, single-use fluid transfer assemblies, a configurable system design with expandable features, and well-developed automation software built on an industry standard platform, enabling performance, flexibility, and speed in bioprocessing.

The system can be tailored for a specific process and flow rate(s) through the selection of low pulsation pumps, offered in three pump combinations, matched fluid transfer assembly sizes, and single-use valve block flow paths aligned with the fluid transfer assemblies. The novel single-use valve manifold design removes limitations caused by pinch valves or clam shell/liner designs, provides error-free fluid transfer assembly insertion, and enables up/down column flow, ensuring safe operation while providing a quicker turn-around time in process suites. The DynaChrom Chromatography System is designed to be column agnostic and can work with any end-user-selected column.

Features & Benefits

• Unique manifold design
–Easy and error-free fluid transfer assembly insertion
–No-pinch-valve design
–Enables up/down column flow
• Wide operational flow range
–Flowrates from 1 L/hr to 1,980 L/hr depending on pump(s) selected
–Fluid transfer assemblies in 1/4-, 3/8-, 1/2-, and 3/4-inch sizes
–Low pulsation pumps
• Zero void volume/ring flush
–Previous phase liquids are instantly flushed at the start of the next phase
–Reduced buffer use
–Improved peak resolution and product yield
• Built on the Emerson DeltaV automation platform
–Ease of tech transfer and data integration
–Ability to leverage existing DeltaV network infrastructure
–Capable of running processes in batch mode
• Chromatography steps and modes of operation
–Affinity, Anion Exchange (AEX), Cation Exchange (CEX), or Reversed Phased Chromatography (RPC)
–Can be configured for bind/elute or flow-through modes of operation
–Can support in-line dilution

Specifications

Official Website

DynaChrom™ Single-Use Chromatography System – Official Website

Brochures

DynaChrom™ Single-Use Chromatography System – Brochures