Ion Exchange Resin

Rp20

Ion exchange chromatography (IEX) is a purification technique that allows for the separation of molecules based on their surface charge. The process exploits the interaction between negatively or positively charged molecules in a sample and an oppositely charged chromatography matrix.

Clear

Thermo Scientificâ„¢ POROSâ„¢ ion exchange (IEX) resins are the industry standard for large-scale polish chromatography applications. POROS IEX resins allows target molecule binding and impurity removal over a broad
range of process conditions, thereby increasing process flexibility and manufacturing throughput. Choosing the right ion exchange resin will help to ensure quality, productivity, and effectiveness of the purification
process. Biomolecules vary in their net charge depending on the solution pH. Select either an anion exchange or
cation exchange resin according the purification step and charged properties of the target molecule.

class

Chromatography Resin

applications

product-type

Consumable

Features & Benefits

The unique features of the POROS chromatography resins Poly (styrene-divinylbenzene) backbone—resulting in linear and scalable performance. The beads are rigid and have a high mechanical strength enabling easy and reproducible scale-up. The polymer backbone is chemically stable allowing for stringent cleaning when needed.
Large throughpores—leading to a reduced mass transfer resistance compared to other resins. Capacity and resolution are maintained over a wide range of linear velocities, thereby establishing a more efficient purification process.
50-micron bead size—providing superior resolution. The smaller particle size results in tighter peaks and smaller elution volumes, helping to overcome volume restrictions in following steps in production.

Specifications

Official Website

Ion Exchange Resin – Official Website

Brochures

Ion Exchange Resin – Brochures